The 28th Advanced School in Life Sciences
The 28th Advanced School in Life Sciences
23-28 October 2022
ORGANIZERS:
Ruth Sperling, The Hebrew University of Jerusalem
Maayan Salton, The Hebrew University of Jerusalem
More details TBA!
23-28 October 2022
ORGANIZERS:
Ruth Sperling, The Hebrew University of Jerusalem
Maayan Salton, The Hebrew University of Jerusalem
More details TBA!
23-27 October 2022
GENERAL DIRECTOR:
Roger Kornberg (Stanford University)
ORGANIZER:
Ruth Sperling, The Hebrew University of Jerusalem
Research during recent decades has identified RNA molecules as key players in biology and medicine. Novel types of large and small RNAs, and novel roles for RNA molecules, not only as informational molecules, but also as enzymes and as regulators of gene expression, have emerged. RNA processing and alternative splicing, major contributors to proteome versatility, play crucial roles in cell identity and development. RNA molecules serve as catalysts and as regulators of chromatin structure, gene expression at different levels, and protein function in diverse pathways. The involvement of RNA molecules in disease-related processes has led to RNA-mediated therapies. For example, manipulation of alternative splicing and gene expression by antisense RNAs enabled breakthroughs in the therapies of rare disease, and mRNA-based vaccines have played a crucial role in the fight against the COVID-19 pandemic. Many challenges lie ahead in deciphering the structure and function of RNA molecules and in the development of additional RNA-based therapies. The RNA School will bring together many of the scientists responsible for the important discoveries, and will support stimulating and fruitful discussions of the major topics.
As part of the school, we will hold the Israeli RNA Society meeting in memory of Prof. Yossi Sperling on 26 October.
SPEAKERS:
Gil Ast, Tel Aviv University
Maria Carmo-Fonseca, University of Lisbon
Chonghui Cheng, Baylor College of Medicine
Matthias W. Hentze, European Molecular Biology Laboratory
Eran Hornstein, Weizmann Institute of Science
Batsheva Kerem, The Hebrew University of Jerusalem
Adrian R. Krainer, Cold Spring Harbor Laboratories
Erez Levanon, Bar-Ilan University
Reinhard Lührmann, Max-Planck-Institute for Biophysical Chemistry
Yael Mandel-Gutfreund, Technion
Hanah Margalit, The Hebrew University of Jerusalem
Lynne E. Maquat, University of Rochester Medical Center
Shulamit Michaeli, Bar-Ilan University
Gideon Rechavi, Sheba Medical Center & Tel Aviv University
Michal Shapira, Ben-Gurion University of the Negev
Yaron Shav-Tal, Bar-Ilan University
Noam Stern-Ginossar, Weizmann Institute of Science
Yehuda Tzfati, The Hebrew University of Jerusalem
Igor Ulitsky, Weizmann Institute of Science
Ada Yonath, Weizmann Institute of Science
General Director: Roger Kornberg (Stanford University)
Directors:
Eran Meshorer (The Hebrew University)
Nissim Benvenisty (The Hebrew University)
Speakers: TBA
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structural biology
Roger D. Kornberg is an American biochemist and professor of structural biology at Stanford University School of Medicine. Kornberg was awarded the Nobel Prize in Chemistry in 2006 for his studies of the process by which genetic information from DNA is copied to RNA, "the molecular basis of eukaryotic transcription.”
General Director: Roger Kornberg (Stanford University)
Signals are transduced from the environment and from within cells to control gene expression and cell fate. Signal transduction underlies many pathologies, including cancer, inflammation, neurological disorders and cardiovascular disease. A majority of drugs target signal transduction pathways. The 25th Advanced School in the Life Sciences will review the field and related studies. Leaders from Israel and abroad will describe the history and current status of their research.
The School honors the memory of Zvi Selinger, ten years after his passing. Selinger was a pioneer in the signal transduction field. His bold hypothesis of a GTPase cycle and brilliant experimental work inspired others, and laid a basis for subsequent research.
Speakers:
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